[HTML][HTML] Molecular cloning and characterization of a novel mouse βPix isoform
T Kim, D Park - Molecules and cells, 2001 - Elsevier
βPix, a Pak-interacting guanine nucleotide exchange factor is known to be involved in the
regulation of Cdc42/Rac GTPases and Pak kinase activity. Currently, three βPix isoforms,
βPix-a,-b, and-c have been reported. In this study, the cDNA of a novel Pix splice variant was
isolated from a mouse brain cDNA library. The cloned βPix isoform, named βPix-d, lacks
leucine zipper domain that is present in other Pix isoforms, and has a 11 amino acid addition
at carboxyl terminus and distinct 3'-UTR. Analysis of the tissue distribution of βpix present …
regulation of Cdc42/Rac GTPases and Pak kinase activity. Currently, three βPix isoforms,
βPix-a,-b, and-c have been reported. In this study, the cDNA of a novel Pix splice variant was
isolated from a mouse brain cDNA library. The cloned βPix isoform, named βPix-d, lacks
leucine zipper domain that is present in other Pix isoforms, and has a 11 amino acid addition
at carboxyl terminus and distinct 3'-UTR. Analysis of the tissue distribution of βpix present …
Molecular cloning and characterization of a novel mouse βPix isoform.
KT Kim Taeho, PD Park Dongeun - 2000 - cabidigitallibrary.org
Abstract βPix, a Pak-interacting guanine nucleotide exchange factor is known to be involved
in the regulation of Cdc42/Rac GTPases and Pak kinase activity. Currently, three βPix
isoforms, βPix-a,-b, and-c have been reported. In this study, the cDNA of a novel Pix splice
variant was isolated from a mouse brain cDNA library. The cloned βPix isoform, named βPix-
d, lacks leucine zipper domain that is present in other Pix isoforms, and has a 11 amino acid
addition at carboxyl terminus and distinct 3′-UTR. Analysis of the tissue distribution of βPix …
in the regulation of Cdc42/Rac GTPases and Pak kinase activity. Currently, three βPix
isoforms, βPix-a,-b, and-c have been reported. In this study, the cDNA of a novel Pix splice
variant was isolated from a mouse brain cDNA library. The cloned βPix isoform, named βPix-
d, lacks leucine zipper domain that is present in other Pix isoforms, and has a 11 amino acid
addition at carboxyl terminus and distinct 3′-UTR. Analysis of the tissue distribution of βPix …
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