… with hypoxic tumors invariably experience poor outcome to treatment. This has led the molecular
imaging community to develop assays for hypoxia … approaches with imaging agents that …

A wide variety of imaging … hypoxia in vivo. In particular, nuclear medicine has seen the
development of several radiolabeled hypoxia markers and is the preferred method for imaging of …

… (SPECT), magnetic resonance imaging (MRI), autoradiography … molecular imaging modalities
with radiolabelled PET and SPECT tracers that are available to measure tumour hypoxia…

… hypoxia could be … Molecular imaging approaches targeting hypoxic cells have shown some
early success in the clinical setting. This review evaluates the evidence for hypoxia imaging …

… to measure tumor hypoxia. Although no method is ideal, molecular imaging has become the
… (SPECT), magnetic resonance imaging (MRI) and optical imaging have become useful tools …

… a variety of molecular probes that have been developed for imaging hypoxia in tumors,
with emphasis on the synthetic aspects. While imaging probes targeting hypoxia have been …

… this invasive procedure with a molecular imaging approach based on selective ligands to
accessible proteins overexpressed at sites of hypoxia. Based on transcriptomic profiling of …

… reporter system, we can image hypoxia-induced molecular events and map their distribution
in vivo with noninvasive PET imaging. This is based on hypoxia-induced increase in HIF-1α …

… disorders, allowing the detection of hypoxic tissue and the prediction of the extent …
hypoxia-directed treatment and provide prognosis relevant imaging. The molecular imaging of …

… emphasis was placed on noninvasive imaging hypoxia with emerging new agents and
new imaging technologies to detect the molecular events that are relevant to tumor hypoxia. …