Molecular knots

SDP Fielden, DA Leigh… - Angewandte Chemie …, 2017 - Wiley Online Library
… The first synthetic molecular trefoil knot was prepared in the late … -molecule knot topologies
have been realized through chemical synthesis. The steric restrictions imposed on molecular

Molecular knots in biology and chemistry

NCH Lim, SE Jackson - Journal of Physics: Condensed Matter, 2015 - iopscience.iop.org
… of molecular knots have been increasingly recognised by scientists from different disciplines.
In this review, we provide an overview on the various molecular knots … intricate molecules. …

Molecular knots

C Dietrich-Buchecker, BX Colasson… - Templates in Chemistry II …, 2005 - Springer
… leading to a large number of molecular knot analogs of 25 [89–90] and more exotic
structures [91]. The intrinsic chirality of a molecular knot was introduced earlier. Chromatographic …

Chemical topology: complex molecular knots, links, and entanglements

RS Forgan, JP Sauvage, JF Stoddart - Chemical Reviews, 2011 - ACS Publications
1.1. History and Background Knots and links are all around us (Figure 1). Be they functional
or decorative, we encounter them constantly, when, for example, tying simple bow knots in …

Template synthesis of molecular knots

JF Ayme, JE Beves, CJ Campbell… - Chemical Society Reviews, 2013 - pubs.rsc.org
… Despite the examples of molecular knots formed using … molecular knots from small molecule
building blocks. The key factors to be considered when designing a route to molecular knots

Knotting and threading of molecules: chemistry and chirality of molecular knots and their assemblies

O Lukin, F Vögtle - Angewandte Chemie International Edition, 2005 - Wiley Online Library
… The first synthesis of a molecular knot was reported in 1989, 22 but the earlier … molecular
knots contributed significantly to a multi-angle view of the problem of assembling synthetic knots

Braiding a molecular knot with eight crossings

JJ Danon, A Krüger, DA Leigh, JF Lemonnier… - Science, 2017 - science.org
… prime knots have been synthesized with small molecules. Most of the molecular knots isolated
to … for the construction of simple small-molecule knots have been successfully developed, …

Tying a molecular knot with optical tweezers

Y Arai, R Yasuda, K Akashi, Y Harada, H Miyata… - Nature, 1999 - nature.com
molecular strand by tying a knot in it, using optical tweezers to manipulate the strand's ends.
We find that actin filaments break at the knot when the knot … a single DNA molecule, opening …

A strategy to synthesize molecular knots and links using the hydrophobic effect

FBL Cougnon, K Caprice, M Pupier… - Journal of the …, 2018 - ACS Publications
… 1), a Solomon link (2), and a trefoil knot (3). We are working on obtaining crystals … molecules
1–3, this work will probably represent the simplest strategy to date to access molecular knots

A synthetic molecular pentafoil knot

JF Ayme, JE Beves, DA Leigh, RT McBurney… - Nature …, 2012 - nature.com
… Here, we report on the synthesis of the most complex non-DNA molecular knot prepared to
… -loop molecular pentafoil knot (five crossing points). The structure and topology of the knot is …