… molecular nature of the general anaesthetic site(s) from a quantitative consideration of data
on the potency of general anaesthetics … the most plausible molecular target for general anaes…

… This paper provides new insights of how general anaesthetic research should be carried
out … I describe previous hypotheses on the mechanism of action of general anaesthetics (GAs) …

… general anaesthetics remain elusive. This review summarizes the remarkable developments
which have occurred in general anaesthetic … lipid membranes, general anaesthetics target …

… General anaesthetics are much more selective than is usually … in general anaesthesia.
Although the role of second messengers remains uncertain, it is now clear that anaesthetics act …

… in our understanding of the mechanisms of general anesthetic action at the molecular,
cellular and neural systems levels has been made. Different molecular targets in various regions …

… as the most likely molecular targets for general anesthetics. The γ-aminobutyric acid type
A (GABA A ) receptors are leading candidates as a primary target of general anesthetics. This …

… transmuted into becoming a definition of a general anaesthetic. This is to confuse what is …
of a general anaesthetic. The drugs that we commonly class as general anaesthetics (Figure 2) …

… , finally, Mechanisms of Anaesthetics and Anaesthesia. The … for anaesthesia mechanisms,
general anaesthesia has become … For example, most general anaesthetics cause respiratory …

… , our understanding of general anesthetic mechanisms has evolved … of scientific disciplines
ranging from molecular biology to cognitive … Molecular mechanisms of general anaesthesia …

… by MAC-equivalent general anaesthetic concentrations if the cells are tonically depolarized
or induced to fire rapidly.This is analogous to the actions of local anaesthetic, antiarrhythmic …