2 天前 - … in the clinical diagnosis and treatments of the disease, pathophysiological
mechanisms of UCPPS, signaling pathways, and molecular targets involved in pelvic nociception. …

5 天前 - … molecules like PACAP or TPRSV1 causing nociception and vasodilation of
meningeal vessels [16]. Evidence suggest that a role of NO is associated with neuropathic pain …

8 天前 - … In the present study, baseline nociceptive thresholds were measured in a murine
model as a reference point, after which nociception and adenosine concentrations were …

16 天前 - … Despite the presumed physiological relevance of the molecular mechanisms that
establish and control the subtle balance between phosphorylated and dephosphorylated …

18 天前 - … Fgf3 expression mitigated nerve injury induced nociceptive hypersensitivity, suggesting
its pivotal … This study thereby advances our understanding of the molecular mechanisms …

21 天前 - … -nociceptive, anti-inflammatory, and skin barrier repair. The mechanism of the
anti-nociceptive … was further investigated and explained by molecular docking site analysis. This …

24 天前 - … on menthol-induced nociception was not affected by a TRPM8 antagonist, suggesting
that TRPM8 modulation is not involved in nicorandil’s mechanism of action. The study …

25 天前 - … mechanisms. For example, CGRP has been shown to stimulate trigeminal afferent
activity and sensitize nociceptive neurons… pain modulation and nociceptive signal generation, …

30 天前 - … cellular-level interactions between nociceptors and the immune system … molecular
mechanism that coordinates immune responses in the skin barrier. Identifying the molecular …

30 天前 - … Conclusion: The S1P/S1PR1 axis plays a pivotal role in the cellular and molecular
mechanisms underlying nociceptive pain. This signaling pathway modulates glial cell …