过去一年中添加的文章,按日期排序

In Vitro and In Vivo Effects of Melatonin-Containing Combinations in Human Pancreatic Ductal Adenocarcinoma

L Zeppa, C Aguzzi, MB Morelli… - Journal of pineal …, 2024 - pubmed.ncbi.nlm.nih.gov
1 天前 - … Moreover, different combinations of treatments reduced tumor mass in the PDAC
mouse model, thus promoting the effect of GEM. In conclusion, a mixture of MLT + CBD + O 2 /…

New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer

C Espinosa-Bustos, J Bertrand, A Villegas-Menares… - Bioorganic …, 2024 - Elsevier
4 天前 - Pancreatic cancer is a highly lethal malignancy characterized by late … from
pancreatic cancer still stands at less than 5 %. Globally, 458 918 new cases of pancreatic cancer

LPCAT2-mediated lipid droplet production supports pancreatic cancer chemoresistance and cell motility

Y Lin, X Zhang, Y Wang, W Yao - International Immunopharmacology, 2024 - Elsevier
4 天前 - … of LD accumulation on pancreatic cancer chemoresistance and cell motility, which
were regulated by the Lands cycle acyltransferase LPCAT2. A xenograft model of mice was …

… the therapeutic potential of a novel series of imidazothiadiazoles targeting focal adhesion kinase (FAK) for pancreatic cancer treatment: Synthesis, mechanistic …

C Pecoraro, D Carbone, F Scianò… - Journal of Drug …, 2024 - Taylor & Francis
4 天前 - Pancreatic ductal adenocarcinoma (PDAC), comprising more than 90% of pancreatic
cancer cases, stands out as one of the deadliest tumors, with a 5-year overall survival rate …

Broussoflavonol B Induces S-Phase Arrest and Apoptosis in Pancreatic Cancer Cells by Modulating the Cell Cycle Checkpoint Through Inhibition of the Aurka/Plk1 …

L Zhang, HC Choe, Z Wang, Y Yang, Z Zhao… - Available at SSRN … - papers.ssrn.com
5 天前 - pancreatic cancer were analyzed. The viability and migration ability of pancreatic
cancer … In vivo experiments, we employed a xenograft mice model to evaluate the anti-cancer

Targeting of immune checkpoint regulator V-domain Ig suppressor of T-cell activation (VISTA) with 89Zr-labelled CI-8993

IJG Burvenich, CW Wichmann, AF McDonald… - European Journal of …, 2024 - Springer
5 天前 - cancer cell line MB49 was obtained from EMD Millipore (SCC148; Temecula, CA).
Capan-2 human pancreatic cancer … in a genetic mouse model expressing chimeric VISTA …

[HTML][HTML] Knockdown of TGF-β in Pancreatic Cancer Helps Ameliorate Gemcitabine Resistance

X Wang, W Su, C Qin, R Gao, S Shao, X Xu… - Frontiers in Bioscience …, 2024 - imrpress.com
6 天前 - … GEM resistance in pancreatic cancer mice. (A) Pancreatic cancer mouse model
was constructed by subcutaneously injecting GEM-resistant PANC-1 cells in mouse axilla. (B) …

A common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

C Bodas, I Felipe, B Chanez, M Lafarga… - bioRxiv, 2024 - biorxiv.org
7 天前 - … our mouse model recapitulates features of human carriers of the CTRB2 exon 6
deletion, we mined publicly available data from the pancreas of … We report a new mouse model

Development of Thermo-responsive materials for pancreatic cancer management

AMSM ElSherbeny - eprints.nottingham.ac.uk
7 天前 - … PANC-1 xenograft subcutaneous mice models. Moreover, … chemotherapy used
in pancreatic cancer treatment into … drug delivery system for pancreatic cancer management. …

[HTML][HTML] In vivo interaction screening reveals liver-derived constraints to metastasis

C Borrelli, M Roberts, D Eletto, MD Hussherr, H Fazilaty… - Nature, 2024 - nature.com
7 天前 - … We identify plexin B2 as a critical host-derived regulator of liver colonization in
colorectal and pancreatic cancer and melanoma syngeneic mouse models. We dissect a …