Mutants of activation-induced cytidine deaminase (AID) and methods of use
M Wang, Z Yang, C Rada, M Neuberger - US Patent 9,683,226, 2017 - Google Patents
The invention provides functional mutants of activation induced cytidine deaminase (AID)
protein that have increased activity as compared to a wild-type AID protein. The invention
also provides nucleic acids encoding the functional AID mutants, and vectors and cells
comprising the nucleic acids. The invention further provides methods of using the functional
mutant AID proteins.
protein that have increased activity as compared to a wild-type AID protein. The invention
also provides nucleic acids encoding the functional AID mutants, and vectors and cells
comprising the nucleic acids. The invention further provides methods of using the functional
mutant AID proteins.
Mutants of activation-induced cytidine deaminase (aid) and methods of use
M Wang, Z Yang, C Rada… - EP Patent App. 10,723,293 …, 2012 - Google Patents
The invention provides functional mutants of activation-induced cytidine deaminase (AID)
protein that have increased activity as compared to a wild-type AID protein. The invention
also provides nucleic acids encoding the functional AID mutants, and vectors and cells
comprising the nucleic acids. The invention further provides methods of using the functional
mutant AID proteins.
protein that have increased activity as compared to a wild-type AID protein. The invention
also provides nucleic acids encoding the functional AID mutants, and vectors and cells
comprising the nucleic acids. The invention further provides methods of using the functional
mutant AID proteins.
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