N, O-Benzamide difluoroboron complexes as near-infrared probes for the detection of β-amyloid and tau fibrils
Chemical Communications, 2020•pubs.rsc.org
In this study, a series of organo difluoroboron probes with a BF2 benzamide moiety was
designed, prepared and evaluated. Among them, 2c displayed the best optical and
biological properties, and may be used as a useful near-infrared fluorescent probe for the
detection of Aβ plaques and neurofibrillary tangles in AD.
designed, prepared and evaluated. Among them, 2c displayed the best optical and
biological properties, and may be used as a useful near-infrared fluorescent probe for the
detection of Aβ plaques and neurofibrillary tangles in AD.
In this study, a series of organo difluoroboron probes with a BF2 benzamide moiety was designed, prepared and evaluated. Among them, 2c displayed the best optical and biological properties, and may be used as a useful near-infrared fluorescent probe for the detection of Aβ plaques and neurofibrillary tangles in AD.
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