Enhanced efficacy of folate-incorporated cholesteryl doxorubicin liposome in folate receptor abundant cancer cell

JS Choi, JW Park, YB Seu, KO Doh - Journal of Drug Delivery Science and …, 2021 - Elsevier
… cholesterol derivatives that showed anticancer activity with longer … A549 (human lung
carcinoma cell line), HeLa (human cervix … were confirmed by MTT assay, carried out using the …

A biomimetic drug delivery system by integrating grapefruit extracellular vesicles and doxorubicin-loaded heparin-based nanoparticles for glioma therapy

W Niu, Q Xiao, X Wang, J Zhu, J Li, X Liang, Y Peng… - Nano …, 2021 - ACS Publications
… In the PE channel, EV-DN2 exhibited better cellular internalization than that of DOX and DNs,
… the brain tumor while the strong fluorescence of Cy7-EV-DN2 that accumulated in the brain …

Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin

G Toffoli, M Hadla, G Corona, I Caligiuri… - …, 2015 - Taylor & Francis
… the efficacy of doxorubicin by actively targeting tumor cells and … deliver DOX with the same
antitumor efficacy as free DOX in … ExoDOX has similar antitumor effect as free DOX but is less …

Exosome mimetics derived from bone marrow mesenchymal stem cells deliver doxorubicin to osteosarcoma in vitro and in vivo

J Wang, M Li, L Jin, P Guo, Z Zhang, C Zhanghuang… - Drug Delivery, 2022 - Taylor & Francis
potent tumor inhibition activity and fewer side effects than free … and carry out the material
exchange between cells by … In summary, the anti-tumor effect of EM-Dox on osteosarcoma tumor-…

Targeted delivery of doxorubicin by SP5-52 peptide conjugated exosome nanoparticles into lung tumor: An in vitro and in vivo study

A Moradi, A Shirangi, M Asadi, M Farokhi… - … of Drug Delivery Science …, 2024 - Elsevier
… in diameter with the ability to carry biomolecules such as proteins, … would have effective
anticancer effect on lung tumor cells. … that nanosomes selectively reduced the tumor cell viability. …

Drug delivery approaches for HuR-targeted therapy for lung cancer

R Raguraman, S Shanmugarama, M Mehta… - Advanced drug delivery …, 2022 - Elsevier
Lung cancer (LC) is often diagnosed at an advanced stage and conventional treatments
for disease management have limitations associated with them. Novel therapeutic targets are …

Exosomes as drug delivery vehicle and contributor of resistance to anticancer drugs

M Chinnappan, A Srivastava, N Amreddy, M Razaq… - Cancer letters, 2020 - Elsevier
… geldanamycin exhibited improved antitumor activity compared … -cell response against lung
cancer was observed with tumor-… enrich doxorubicin specifically in breast cancer cells thereby …

Biocompatible exosomes nanodrug cargo for cancer cell bioimaging and drug delivery

A Qambrani, FU Rehman, T Tanziela… - Biomedical …, 2021 - iopscience.iop.org
… These particles possess the ability to carry other small … immunity in patients with advanced
non-small cell lung cancer [… doxorubicin (Dox) to cancer cells for efficient theranostics. …

Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
… in the tumor, and enhanced antitumor activity with minimal off… (nanosomes) by the recipient
lung cancer cells H1299 was … by reducing doxorubicin resistance, the GIONs demonstrated …

Exosomes as theranostics for lung cancer

A Srivastava, N Amreddy, M Razaq, R Towner… - Advances in cancer …, 2018 - Elsevier
Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung
cancer cells… that we can deliver anticancer therapeutics (Dox) to lung cancer cells (H1299 and …