Naringin inhibits ROS‐activated MAPK pathway in high glucose‐induced injuries in H9c2 cardiac cells
J Chen, R Guo, H Yan, L Tian, Q You… - Basic & Clinical …, 2014 - Wiley Online Library
Naringin, an active flavonoid isolated from citrus fruit extracts, exhibits biological and
pharmacological properties, such as antioxidant activity and antidiabetic effect. Mitogen‐
activated protein kinase (MAPK) signalling pathway has been shown to participate in
hyperglycaemia‐induced injury. The present study tested the hypothesis that naringin
protects against high glucose (HG)‐induced injuries by inhibiting MAPK pathway in H9c2
cardiac cells. To examine this, the cells were treated with 35 mM glucose (HG) for 24 hr to …
pharmacological properties, such as antioxidant activity and antidiabetic effect. Mitogen‐
activated protein kinase (MAPK) signalling pathway has been shown to participate in
hyperglycaemia‐induced injury. The present study tested the hypothesis that naringin
protects against high glucose (HG)‐induced injuries by inhibiting MAPK pathway in H9c2
cardiac cells. To examine this, the cells were treated with 35 mM glucose (HG) for 24 hr to …
Naringin inhibits ROS-activated MAPK pathway in high glucose-induced injuries in H9c2 cardiac cells.
CJF Chen JingFu, GRM Guo RunMin, YH Yan Hai… - 2014 - cabidigitallibrary.org
Naringin, an active flavonoid isolated from citrus fruit extracts, exhibits biological and
pharmacological properties, such as antioxidant activity and antidiabetic effect. Mitogen-
activated protein kinase (MAPK) signalling pathway has been shown to participate in
hyperglycaemia-induced injury. The present study tested the hypothesis that naringin
protects against high glucose (HG)-induced injuries by inhibiting MAPK pathway in H9c2
cardiac cells. To examine this, the cells were treated with 35 mM glucose (HG) for 24 hr to …
pharmacological properties, such as antioxidant activity and antidiabetic effect. Mitogen-
activated protein kinase (MAPK) signalling pathway has been shown to participate in
hyperglycaemia-induced injury. The present study tested the hypothesis that naringin
protects against high glucose (HG)-induced injuries by inhibiting MAPK pathway in H9c2
cardiac cells. To examine this, the cells were treated with 35 mM glucose (HG) for 24 hr to …
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