Nerve ultrasound protocol in differentiating chronic immune‐mediated neuropathies
A Kerasnoudis, K Pitarokoili, A Haghikia… - Muscle & …, 2016 - Wiley Online Library
A Kerasnoudis, K Pitarokoili, A Haghikia, R Gold, MS Yoon
Muscle & Nerve, 2016•Wiley Online LibraryIntroduction: In this study we evaluated a new neuropathy ultrasound protocol (NUP) for
differentiating chronic immune‐mediated neuropathies. Methods: The NUP was evaluated in
110 patients with clinical presentations of chronic immune‐mediated neuropathy. All
patients were first evaluated clinically and electrophysiologically and divided into 4
polyneuropathy groups:(a) symmetric demyelinating;(b) symmetric axonal;(c) asymmetric
demyelinating; and (d) asymmetric axonal. During step 2, the NUP was evaluated …
differentiating chronic immune‐mediated neuropathies. Methods: The NUP was evaluated in
110 patients with clinical presentations of chronic immune‐mediated neuropathy. All
patients were first evaluated clinically and electrophysiologically and divided into 4
polyneuropathy groups:(a) symmetric demyelinating;(b) symmetric axonal;(c) asymmetric
demyelinating; and (d) asymmetric axonal. During step 2, the NUP was evaluated …
Abstract
Introduction: In this study we evaluated a new neuropathy ultrasound protocol (NUP) for differentiating chronic immune‐mediated neuropathies. Methods: The NUP was evaluated in 110 patients with clinical presentations of chronic immune‐mediated neuropathy. All patients were first evaluated clinically and electrophysiologically and divided into 4 polyneuropathy groups: (a) symmetric demyelinating; (b) symmetric axonal; (c) asymmetric demyelinating; and (d) asymmetric axonal. During step 2, the NUP was evaluated prospectively for all 4 study groups. Results: Overall, the NUP led to correct classification in 42 of 49 (85.7%) patients with chronic inflammatory demyelinating polyneuropathy (CIDP), 13 of 15 (86.9%) with multifocal motor neuropathy (MMN), and 5 of 5 (100%) with multifocal‐acquired demyelinating sensory and motor neuropathy (MADSAM). The NUP had >80% sensitivity and specificity in distinguishing CIDP, MMN, and MADSAM in all 4 study groups. Conclusions: The NUP is a useful addition in the differential diagnosis of chronic immune‐mediated neuropathies in everyday practice. Muscle Nerve 54: 864–871, 2016
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