Context People experiencing possible prodromal symptoms of psychosis have a very high
risk of developing the disorder, but it is not possible to predict, on the basis of their
presenting clinical features, which individuals will subsequently become psychotic. Recent
neuroimaging studies suggest that there are volumetric differences between individuals at
ultra-high risk (UHR) for psychosis who later develop psychotic disorder and those who do
not. However, the samples examined to date have been small, and the findings have been …