Although maternal cigarette smoking during pregnancy is a well-documented risk factor for a
variety of adverse pregnancy outcomes, how prenatal cigarette smoke exposure affects
postnatal neurobehavioral/cognitive development remains poorly defined. In order to
investigate the cause of an altered behavioral phenotype, mice developmentally exposed to
a paradigm of 'active'maternal cigarette smoke is needed. Accordingly, cigarette smoke
exposed (CSE) and air-exposed C57BL/6J mice were treated for 6h per day in paired …