[PDF][PDF] Neurodevelopmental and visual outcomes of preterm infants with retinopathy of prematurity

MYA Al-Hindi - 2010 - collectionscanada.gc.ca
2010collectionscanada.gc.ca
Objective: To examine the neurodevelopmental and visual outcomes of children who
developed severe retinopathy of prematurity (ROP) at 36 months corrected age. Methods:
This was a retrospective cohort study with prospective neurodevelopmental and visual
follow up carried out on eligible infants born preterm≤ 28 weeks gestation and/or birth
weight≤ 1250 grams between 1996 and 2004. Results: Of the 677 infants followed, 568 had
no/mild ROP and 109 had severe ROP. The risk of developing severe Neurodevelopmental …
Abstract
Objective: To examine the neurodevelopmental and visual outcomes of children who developed severe retinopathy of prematurity (ROP) at 36 months corrected age.
Methods: This was a retrospective cohort study with prospective neurodevelopmental and visual follow up carried out on eligible infants born preterm≤ 28 weeks gestation and/or birth weight≤ 1250 grams between 1996 and 2004.
Results: Of the 677 infants followed, 568 had no/mild ROP and 109 had severe ROP. The risk of developing severe Neurodevelopmental impairment among the severe ROP group was 3.4 times (95% CI 2.32-4.98) of the no/mild ROP group. Gestational age, severe brain injury and severe ROP were independent risk factors for severe Neurodevelopmental impairment. All visual morbidities were higher in the severe ROP group.
Conclusion: Severe ROP is linked to increased risk of severe Neurodevelopmental impairment and visual morbidities.
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