Bone marrow (BM) derived mesenchymal stem cells (MSC) differentiate into cells of the
mesodermal lineage but also, under certain experimental circumstances, into cells of the
neuronal and glial lineage. Their therapeutic translation has been significantly boosted by
the demonstration that MSC display significant also anti-proliferative, anti-inflammatory and
anti-apoptotic features. These properties have been exploited in the effective treatment of
experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis …