Neutrophils Engraftment Delay During Tigecycline Treatment in 2 Bone Marrow–transplanted Patients
N Maximova, D Zanon, F Verzegnassi… - Journal of Pediatric …, 2013 - journals.lww.com
Background: Tigecycline is the first available drug of glycylcycline family. Because of recent
introduction, some of its adverse effects could be still unexplored. Observation: We report the
cases of 2 boys who underwent an allogenic bone marrow transplantation for acute myeloid
leukemia and were treated with tigecycline. Erythrocyte and platelet engraftment followed a
normal course, but the neutrophil count remained low despite the increase in leukocyte
count. After tigecycline interruption, the neutrophil count rapidly raised in both cases …
introduction, some of its adverse effects could be still unexplored. Observation: We report the
cases of 2 boys who underwent an allogenic bone marrow transplantation for acute myeloid
leukemia and were treated with tigecycline. Erythrocyte and platelet engraftment followed a
normal course, but the neutrophil count remained low despite the increase in leukocyte
count. After tigecycline interruption, the neutrophil count rapidly raised in both cases …
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