过去一年中添加的文章,按日期排序

Sex-Related Determinants of Exercise Intolerance in HFpEF: Not Just a Matter of the Heart!

L Del Punta, N De Biase, NR Pugliese - JACC: Advances, 2024 - jacc.org
8 天前 - therapy, with few exceptions. As the outcomes of these patients remain relatively
poor, 1 deeper insight into … would be crucial to implementing new therapeutic strategies. The “…

Hyperphosphatemia in Chronic Kidney Disease: The Search for New Treatment Paradigms and the Role of Tenapanor

V Cernaro, E Longhitano, C Casuscelli… - … of Nephrology and …, 2024 - Taylor & Francis
25 天前 - … events, thereby limiting their prescription and therapeutic adherence. There is a
growing focus on exploring novel therapeutic strategies in this context. The current discussion …

Circadian dynamics and matrix protein turnover in the kidney glomerulus

R Preston - 2024 - escholar.manchester.ac.uk
28 天前 - … for kidney fibrosis, or serve as potential therapeutic targets, to ameliorate or prevent
new insight into the temporal regulation of the kidney matrix and the pathogenesis of …

# 930 Elevated glucose in kidney organoids induces epithelial detachment driven by proinflammatory cytokines

G Spennati, MC Regier, HH Ward, V Das… - Nephrology Dialysis …, 2024 - academic.oup.com
29 天前 - … To further validate these findings and investigate possible therapeutic strategies, …
, this new experimental model in-vitro offers up new insights into the pathophysiology of …

Drugs in Development to Treat IgA Nephropathy

L Del Vecchio, M Allinovi, S Comolli, S Peiti, C Rimoldi… - Drugs, 2024 - Springer
29 天前 - treatment targets have been identified and new drugs developed. In this narrative
… clinical development for the treatment of IgA nephropathy. As a search strategy, we used …

Renal physiology: epithelial cell mechanics

F Di Sole, K Laghmani, V Babich - Frontiers in Physiology, 2024 - frontiersin.org
32 天前 - … , new insights into molecular mechanisms underlying sodium balance. Furthermore,
Liu et al. studied how potassium (K+) channel activity affects membrane potential in renal …

The role of long non‐coding RNAs in the development of diabetic kidney disease and the involved clinical application

Q Hou, B Yi - Diabetes/Metabolism Research and Reviews, 2024 - Wiley Online Library
46 天前 - renal disease. However, there are still gaps in our understanding of the pathophysiology
of DKD, and both current clinical diagnostic methods and treatment strategies have …

Kidney Failure in Pauci-immune Crescentic Glomerulonephritis: Rationale for Immunosuppression to Improve Kidney Outcome

F Aqeel, D Geetha - Current rheumatology reports, 2024 - Springer
46 天前 - … The overall treatment of pauci-immune … New insights into the pathogenesis of AAV
coupled with the successful completion of randomized trials have expanded the therapeutic

Chinese botanical drugs targeting mitophagy to alleviate diabetic kidney disease, a comprehensive review

L Ma, J Li, X Zhang, W Zhang, C Jiang… - Frontiers in …, 2024 - frontiersin.org
53 天前 - therapeutic strategies can inhibit the deterioration of DKD. The present strategies
for treating … restore impaired mitophagy may provide innovative therapeutic strategy for DKD. …

Diabetes Mellitus: Understanding the Pathophysiology and Therapeutic Strategies

A Gupta, A Yadav, DK Jain - Journal of Clinical Advances and Research …, 2024 - jcarr.in
73 天前 - into three types: type 1, type 2 and gestational diabetes. Each has its own characteristics
and requires different management strategies. [6] … for tailoring management strategies. …