过去一年中添加的文章,按日期排序

From Lab Bench to Hope: Emerging Gene Therapies in Clinical Trials for Alzheimer's Disease

A Ortega, B Chernicki, G Ou, MS Parmar - Molecular Neurobiology, 2024 - Springer
5 天前 - Alzheimer’s disease is a progressive neurodegenerative disorder that affects memory
and cognitive … Current treatments focus on the management of symptoms, as no effective …

Tyrosine Kinases as Multifaceted Drug Targets for Therapeutic Intervention in the Treatment of Alzheimer's Disease

M Stevenson - 2024 - repository.library.georgetown.edu
9 天前 - disease of aging for which there currently exists no cure. Clinical symptoms include
cognitive impairment, loss of memory… skills, and psychological symptoms such as anxiety …

[HTML][HTML] Molecular Mechanisms of Dementia 2.0

M Cantone - International Journal of Molecular Sciences, 2024 - mdpi.com
10 天前 - … early as possible, before symptoms manifest, is the major … patients with memory
decline at early stages of cognitive … DMN was higher; the SN was not different; and the CEN was …

[HTML][HTML] Current therapeutics for Alzheimer's disease and clinical trials

D Xiao, C Zhang - Exploration of Neuroscience, 2024 - explorationpub.com
11 天前 - disease, characterized by memory loss and cognitive decline. … Among the few clinical
trials targeting non-cognitive symptoms… of synapse damage or loss in Alzheimer's disease. …

[HTML][HTML] Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study

EW Paolillo, KB Casaletto, AL Clark, JC Taylor… - JMIR aging, 2024 - aging.jmir.org
11 天前 - … sensitivity to clinical severity in Alzheimer disease [17-25]; … neurobehavioral
symptoms at the prodromal stage (ie, no … A composite memory z score was created by taking the …

Robust and interpretable AI-guided marker for early dementia prediction in real-world clinical settings

Z Kourtzi - 2024 - repository.cam.ac.uk
14 天前 - … predictors (cognitive tests, grey matter atrophy) that are common across … to
Alzheimer’s Disease (AD). PPM generalizes from research to real-world patient data across memory

[HTML][HTML] Behaviour Hallmarks in Alzheimer's Disease 5xFAD Mouse Model

MS Pádua, JL Guil-Guerrero, PA Lopes - International Journal of …, 2024 - mdpi.com
18 天前 - cognitive functions, encompassing learning and memory … mice exhibit no signs of
associative learning and memory … , mice start to develop learning and memory impairments [48…

Unveiling the Complex Role of Exosomes in Alzheimer's Disease

M Sun, Z Chen - Journal of Inflammation Research, 2024 - Taylor & Francis
18 天前 - … the symptoms of AD, but a cure for the illness has not yet … Treatment for Alzheimer’s
disease often involves targeting … , hence protecting memory and cognitive abilities. Citation…

Parental History of Memory Impairment and β-Amyloid in Cognitively Unimpaired Older Adults

M Seto, TJ Hohman, EC Mormino, KV Papp… - JAMA …, 2024 - jamanetwork.com
20 天前 - … of late-onset Alzheimer disease, but not paternal, predisposes … and paternal age
at symptom onset in terms of brain Aβ … cognition, and we could not assess the association of …

[PDF][PDF] UNDERSTANDING THE DEVELOPMENT OF ALZHEIMER'S DİSEASE

A Kabal - MOLECULAR - tedankara.k12.tr
22 天前 - … the development of Alzheimer's Disease, its causes, and … indicate memory loss and
diminishing cognitive functions. … still no known cure for it. Therefore, it is safe to assume that …