Nonhuman primate lung decellularization and recellularization using a specialized large-organ bioreactor

RW Bonvillain, ME Scarritt, NC Pashos… - JoVE (Journal of …, 2013 - jove.com
There are an insufficient number of lungs available to meet current and future organ
transplantation needs. Bioartificial tissue regeneration is an attractive alternative to classic
organ transplantation. This technology utilizes an organ's natural biological extracellular
matrix (ECM) as a scaffold onto which autologous or stem/progenitor cells may be seeded
and cultured in such a way that facilitates regeneration of the original tissue. The natural
ECM is isolated by a process called decellularization. Decellularization is accomplished by …
以上显示的是最相近的搜索结果。 查看全部搜索结果