2 天前 - … non-viral delivery system, lipid nanoparticles (LNPs) were approved by the FDA,
propelling the advancements of gene therapy… synergy of gene therapy and drug therapy. This …

3 天前 - … genes, and then the top correlated genes were tested for further evaluation of
knock-out effects. The nonviral … exons 14 and 16 of the GLB1 gene into SH-SY5Y cells led to the …

3 天前 - … of gene therapies can generally be classified into two methods: viral and non-viral …
are also known as transduction technologies while non-viral vectors can be done by either …

3 天前 - … gene delivery (eg, direct infusion of viral or non-viral vectors with no modifications
on capsid, envelope, or nanoparticles), and cell therapy … The preclinical gene therapy …

3 天前 - … Moreover, in more than half of these cases, the frameshift site locates far upstream
from the stop codon of the 0 reading frame, which is nonviral-like. Using dual luciferase …

4 天前 - … gene therapy technologies. These include the use of viral vectors to deliver functional
genes… and hemophilia, and the development of targeted gene-editing tools like zinc finger …

4 天前 - … 14 gene therapy products. With the increasing interest in gene therapy, feasible
gene … delivery vectors can be divided into viral and non-viral delivery vectors. For example, …

4 天前 - … non-viral delivery systems for gene editing of HSCs could significantly enhance the
therapeutic … guidance for researchers working on gene therapy applications involving HSCs. …

7 天前 - … The application progresses of nanomedicines, which includes nanoantitumor
drugs, nanopeptide–protein drugs, and nanoformulations of nonviral vector gene drugs, are …

8 天前 - … research, especially in gene therapy, are significantly … of new compounds,
gene-editing techniques, and gene loci offering … viral or non-viral vectors to correct genetic defects …