Noradrenergic pain modulation
A Pertovaara - Progress in neurobiology, 2006 - Elsevier
… extended our understanding of noradrenergic pain modulatory mechanisms. The … of
noradrenergic pain regulatory mechanisms both in health and disease. Since the perception of pain …
noradrenergic pain regulatory mechanisms both in health and disease. Since the perception of pain …
Noradrenergic Locus Coeruleus pathways in pain modulation
M Llorca-Torralba, G Borges, F Neto, JA Mico… - Neuroscience, 2016 - Elsevier
… Thus, the noradrenergic system appears to modulate different components of the pain … the
data available regarding the noradrenergic system in relation to pain, particularly focusing on …
data available regarding the noradrenergic system in relation to pain, particularly focusing on …
The noradrenergic pain regulation system: a potential target for pain therapy
A Pertovaara - European journal of pharmacology, 2013 - Elsevier
… α 2C -adrenoceptor in pain modulation is not yet quite clear. … The intrinsic noradrenergic
pain regulatory system in the … stimulus-evoked pain behavior in animals without sustained pain (…
pain regulatory system in the … stimulus-evoked pain behavior in animals without sustained pain (…
Descending monoaminergic pain modulation: bidirectional control and clinical relevance
EE Benarroch - Neurology, 2008 - AAN Enterprises
… The noradrenergic innervation of the dorsal horn originates … Whereas noradrenergic axon
terminals innervate the cell … mechanism for noradrenergic modulation of neurotransmitter …
terminals innervate the cell … mechanism for noradrenergic modulation of neurotransmitter …
Descending noradrenergic influences on pain
SL Jones - Progress in brain research, 1991 - Elsevier
… all been suggested as possible sources of the spinal noradrenergic (NA) innervation involved
in the centrifugal modulation of spinal nociceptive transmission. Several lines of evidence …
in the centrifugal modulation of spinal nociceptive transmission. Several lines of evidence …
Increased noradrenergic neurotransmission to a pain facilitatory area of the brain is implicated in facilitation of chronic pain
I Martins, P Carvalho, MG de Vries… - …, 2015 - pubs.asahq.org
… the fact that chronic pain is … noradrenergic input to the DRt occurs on nociceptive stimulation
in the spared nerve injury (SNI) model of neuropathic pain and contributes to increased pain …
in the spared nerve injury (SNI) model of neuropathic pain and contributes to increased pain …
Evidence for pain modulation by pre-and postsynaptic noradrenergic receptors in the medulla oblongata
J Sagen, HK Proudfit - Brain research, 1985 - Elsevier
… in the NRM and their role in the modulation of pain sensitivity. The results of these experiments
are … alpha-1 noradrenergic receptors may be involved in the modulation of nociception. …
are … alpha-1 noradrenergic receptors may be involved in the modulation of nociception. …
Descending pain modulation and chronification of pain
MH Ossipov, K Morimura, F Porreca - Current opinion in …, 2014 - journals.lww.com
… Taken together, these observations indicate an important serotonergic role for bidirectional
pain modulation. Descending noradrenergic pain modulation Descending noradrenergic …
pain modulation. Descending noradrenergic pain modulation Descending noradrenergic …
Pharmacologic evidence for the modulation of nociception by noradrenergic neurons
HK Proudfit - Progress in brain research, 1988 - Elsevier
… The NA neurons located in the A1 nucleus, part of the lateral reticular nucleus of the
ventrolateral medulla, constitute a second NA pain modulation system. Electrical or chemical …
ventrolateral medulla, constitute a second NA pain modulation system. Electrical or chemical …
The noradrenergic locus coeruleus as a chronic pain generator
BK Taylor, KN Westlund - Journal of neuroscience research, 2017 - Wiley Online Library
… Therefore, we speculate that trigeminal nerve injury shifts pain modulation within the
noradrenergic LC–mPFC circuit from inhibition to excitation—that perhaps while the LC typically …
noradrenergic LC–mPFC circuit from inhibition to excitation—that perhaps while the LC typically …
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