… was highly expressed at the stage in which myoblasts are undergoing fusion, we examined
myoferlin expression in primary cultured myoblasts using confocal microscopy. Myoferlin …

… Myoferlin is highly expressed in myoblasts that undergoing … and regeneration require
the fusion of myoblast to the … myoferlin GFP reporter is normally expressed in myoblasts but …

… iterative fusion of differentiated myoblasts common to all skeletal muscle. Knowledge of this
process has particular relevance to the treatment of wasting of specific muscle groups due to …

… myoferlin have been well characterized in myoblast fusion. … Therefore, we followed the
common protocol as described in … , highlighting that myoblast fusion is not only required during …

… A significant fusion defect was recapitulated in isolated myoblasts … Mechanistically, we
show that GRAF1 and 2 facilitate myoblast fusion, … Normal myoblast fusion requires myoferlin …

… fusion and be required for muscle regeneration. These observations contrast with the findings
that muscle develops normally … muscle myotube fusion and the related protein, myoferlin, …

… the fusion of two opposed lipid bilayers. Furthermore, myoferlin interacts with EHD2 to regulate
myoblast fusion … kinase receptors requires myoferlin, including VEGFR-2 and Tie-2. Acute …

… IGF1 receptor recycling is required for normal myogenesis and that myoferlin is a critical …
myoblast fusion, we treated freshly isolated and cultured myoblasts from wild-type and myoferlin…

… Myoferlin and dysferlin regulate myoblast fusion and muscle membrane resealing, respectively.
Correspondingly, myoferlin … inhibits myoblast fusion, and EHD2 is required for normal …

… myoblasts and required for efficient myoblast fusion to myotubes. We found that myoferlin …
In contrast to normal myoblasts, myoferlin null myoblasts accumulate labeled transferrin and …