Nose-to-brain drug delivery for the treatment of CNS disease: New development and strategies

L Du, L Chen, F Liu, W Wang, H Huang - International Review of …, 2023 - Elsevier
Delivering drugs to the brain has always been a challenging task due to the restrictive
properties of the blood-brain barrier (BBB). Intranasal delivery is therefore emerging as an
efficient method of administration, making it easy to self-administration and thus provides a
non-invasive and painless alternative to oral and parenteral administration for delivering
therapeutics to the central nervous system (CNS). Recently, drug formulations have been
developed to further enhance this nose-to-brain transport, primarily using nanoparticles …
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