Novel IFNγ homologue identified in Nile tilapia (Oreochromis niloticus) links with immune response in gills under different stimuli
J Velázquez, J Acosta, N Herrera, A Morales… - Fish & shellfish …, 2017 - Elsevier
Interferon gamma (IFN-γ) has important roles in both innate and adaptive immune
responses. This cytokine plays a very important role in defining Th1 immune response in all
vertebrates. In the present study, we identified and isolated for the first time the gene coding
for Nile tilapia (Oreochromis niloticus) IFNγ from spleen lymphocytes. The isolated tilapia
IFNγ has between 24 and 62% of amino acid identity as compared to reported sequences
for other teleost fishes. It has close phylogenetic relationships with IFNγ molecules …
responses. This cytokine plays a very important role in defining Th1 immune response in all
vertebrates. In the present study, we identified and isolated for the first time the gene coding
for Nile tilapia (Oreochromis niloticus) IFNγ from spleen lymphocytes. The isolated tilapia
IFNγ has between 24 and 62% of amino acid identity as compared to reported sequences
for other teleost fishes. It has close phylogenetic relationships with IFNγ molecules …
[引用][C] Novel IFNγ homologue identified in Nile tilapia (Oreochromis niloticus) links with immune response in gills under different stimuli
J Acosta, N Herrera, A Morales, F Herrera… - Fish and Shellfish …, 2017 - Elsevier Ltd
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