Novel circular RNAs expressed in brain microvascular endothelial cells after oxygen-glucose deprivation/recovery

W Liu, C Jia, L Luo, HL Wang, XL Min… - Neural regeneration …, 2019 - journals.lww.com
Circular RNAs (circRNAs) are generated by head-to-tail splicing and are ubiquitously
expressed in all multicellular organisms. Their important biological functions are
increasingly recognized. Cerebral ischemia reperfusion injury-induced brain microvascular
endothelial cell dysfunction is an initial stage of blood-brain barrier disruption. The
expression profile and potential function of circRNAs in brain microvascular endothelial cells
is unknown. Rat brain microvascular endothelial cells were extracted and cultured in …
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