… Survival curves of the 756 pediatric patients with 11q23/MLL-rearranged AML included in
this study. The probability of overall survival (pOS) at 5 years from diagnosis was 56% ± 2% (…

… Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia
: results of an international retrospective study. Blood 114 : 2489-2496, 2009 45 Rubnitz JE, …

… Pediatric acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease.
In addition to the patient's initial response to treatment, its prognosis is … subgroups of AML. …

… over the past decades, pediatric acute myeloid leukemia (AML) is still a life-… results
show that RUNX1 mutations also defined a distinct subgroup with poor outcome in childhood …

… Apart from the genetic- and phenotype-based subgroup analyses, which limited the power
of the results within the minor genetic subgroups, further limitations of our study include the …

… who had been treated for pediatric tumors as well as breast … may portend worse outcomes
in pediatric cases [14,23]. A limitation … over that time period or their effects on patient outcomes. …

… prognosis of patients with MLL-r leukemia [5,10] or is only beneficial to a defined subgroup
… infants, with few studies evaluating the effects of HSCT in non-infant children (aged >1 year) …

… Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia:
results of an international retrospective study. Blood 2009; 114: 2489–2496. …

… outcomes in pediatric and adult acute myeloid leukemia. However… be screened for the
favorable prognostic subgroups t(1,11)(… is a heterogeneous group of leukemias that result from the …

… reported results of a very large collaborative study of children … (8) or into the separate “11q23/KMT2A-other”
subgroup that … group and identified two novel subgroups with recurrent 11q23…