On‐chip determination of tissue‐specific metastatic potential of breast cancer cells
B Firatligil‐Yildirir, G Bati‐Ayaz… - Biotechnology and …, 2021 - Wiley Online Library
Metastasis is one of the major obstacles for breast cancer patients. Limitations of current
models demand the development of custom platforms to predict metastatic potential and
homing choices of cancer cells. Here, two organ‐on‐chip platforms, invasion/chemotaxis (IC‐
chip) and extravasation (EX‐chip) were used for the quantitative assessment of invasion and
extravasation towards specific tissues. Lung, liver and breast microenvironments were
simulated in the chips using tissue‐specific cells embedded in matrigel. In the IC‐chip …
models demand the development of custom platforms to predict metastatic potential and
homing choices of cancer cells. Here, two organ‐on‐chip platforms, invasion/chemotaxis (IC‐
chip) and extravasation (EX‐chip) were used for the quantitative assessment of invasion and
extravasation towards specific tissues. Lung, liver and breast microenvironments were
simulated in the chips using tissue‐specific cells embedded in matrigel. In the IC‐chip …
On-chip determination of tissue-specific metastatic potential of breast cancer cells
B Fıratlıgil Yıldırır, G Batı Ayaz, İ Tahmaz… - Biotechnology and …, 2021 - gcris.iyte.edu.tr
Metastasis is one of the major obstacles for breast cancer patients. Limitations of current
models demand the development of custom platforms to predict metastatic potential and
homing choices of cancer cells. Here, two organ-on-chip platforms, invasion/chemotaxis (IC-
chip) and extravasation (EX-chip) were used for the quantitative assessment of invasion and
extravasation towards specific tissues. Lung, liver and breast microenvironments were
simulated in the chips using tissue-specific cells embedded in matrigel. In the IC-chip …
models demand the development of custom platforms to predict metastatic potential and
homing choices of cancer cells. Here, two organ-on-chip platforms, invasion/chemotaxis (IC-
chip) and extravasation (EX-chip) were used for the quantitative assessment of invasion and
extravasation towards specific tissues. Lung, liver and breast microenvironments were
simulated in the chips using tissue-specific cells embedded in matrigel. In the IC-chip …
以上显示的是最相近的搜索结果。 查看全部搜索结果