The oocyte is a unique and highly specialized cell responsible for creating, activating, and
controlling the embryonic genome, as well as supporting basic processes such as cellular
homeostasis, metabolism, and cell cycle progression in the early embryo. During oogenesis,
the oocyte accumulates a myriad of factors to execute these processes. Oogenesis is
critically dependent upon correct oocyte–follicle cell interactions. Disruptions in oogenesis
through environmental factors and changes in maternal health and physiology can …