Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study
G Gilligan, R Panico, J Lazos, R Morelatto… - Oral …, 2023 - Wiley Online Library
G Gilligan, R Panico, J Lazos, R Morelatto, P Belardinelli, MI Criscuolo, N Bolesina…
Oral Diseases, 2023•Wiley Online LibraryObjective To determine the frequency of oral squamous cell carcinoma (OSCC) associated
or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and
traditional risk factors in Latin America. Methods A retrospective observational study was
conducted in 17 Latin American centres. There were included cases of OSCC, analysing
age, gender, OSCC and their association with previous OPMD. Clinicopathological
variables were retrieved. The condition of sequential‐OSCC versus OSCC‐de novo (OSCC …
or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and
traditional risk factors in Latin America. Methods A retrospective observational study was
conducted in 17 Latin American centres. There were included cases of OSCC, analysing
age, gender, OSCC and their association with previous OPMD. Clinicopathological
variables were retrieved. The condition of sequential‐OSCC versus OSCC‐de novo (OSCC …
Objective
To determine the frequency of oral squamous cell carcinoma (OSCC) associated or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and traditional risk factors in Latin America.
Methods
A retrospective observational study was conducted in 17 Latin American centres. There were included cases of OSCC, analysing age, gender, OSCC and their association with previous OPMD. Clinicopathological variables were retrieved. The condition of sequential‐OSCC versus OSCC‐de novo (OSCC‐dn) was analysed concerning the aforementioned variables. Quantitative variables were analysed using Student's t‐test, and qualitative variables with chi‐square.
Results
In total, 2705 OSCC were included with a mean age of 62.8 years old. 55.8% were men. 53.75% of the patients were smokers and 38% were common drinkers. The lateral tongue border was the most affected site (24.65%). There were regional variations in OPMD, being leukoplakia the most frequent. Of the overall 2705 OSCC cases, 81.4% corresponded to OSCC‐dn, while s‐OSCC were 18.6%. Regarding lip vermillion SCC, 35.7% corresponded to de novo lip SCC and 64.3% were associated with previous OPMD.
Conclusions
In Latin America, OSCC‐dn seems to be more frequent with regional variations of some clinical and histopathological features. Further prospective studies are needed to analyse this phenomenon.
Wiley Online Library以上显示的是最相近的搜索结果。 查看全部搜索结果