过去一年中添加的文章,按日期排序

[HTML][HTML] The Role of Mitochondria in Diabetic Kidney Disease and Potential Therapeutic Targets

M Takasu, S Kishi, H Nagasu, K Kidokoro… - Kidney International …, 2024 - Elsevier
7 天前 - … SGLT-2 inhibitors and GLP-1 receptor agonists, already in clinical use, have also
been shown to be protective for mitochondria, and Nrf2 activation and mitochondrial dynamics …

Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy

J Samarin, H Nuskova, P Fabrowski, M Malz… - bioRxiv, 2024 - biorxiv.org
8 天前 - … toxicity to healthy tissues. These findings underscore the 51 therapeutic potential of
… Leveraging this reduced ability to manage and adapt to oxidative stress, we conducted 110 …

Menstrual Blood-Derived Endometrial Stem Cells Ameliorate Ovarian Senescence by Relieving Oxidative Stress-Induced Inflammation

H Song, R Zhang, Y Liu, J Wu, W Fan, J Wu, Y Liu… - Reproductive …, 2024 - Springer
10 天前 - … D-gal-induced oxidative stress and chronic inflammation. … glycation products and
promoting oxidative stress [21]. Recent … that D-gal-induced oxidative stress leads to systemic …

FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway

M Fang, L Lu, J Lou, J Ou, Q Yu, X Tao, J Zhu… - Molecular …, 2024 - Springer
14 天前 - … as excessive oxidative stress [18,19,20]. Therefore, targeting neuroinflammation
and oxidative stress induced by microglial activation can serve as efficient therapeutic targets …

[HTML][HTML] Dapagliflozin mitigates cellular stress and inflammation through PI3K/AKT pathway modulation in cardiomyocytes, aortic endothelial cells, and stem cell …

FR Alsereidi, Z Khashim, H Marzook… - Cardiovascular …, 2024 - Springer
17 天前 - … elucidate the multifaceted therapeutic potential of DAPA … , and cellular stress
through the activation of the AKT pathway … that ISO induces oxidative stress and disrupts cellular …

[HTML][HTML] Revealing Secrets of Blue Zones

NN Ulusu - Frontiers in Pharmacology - frontiersin.org
18 天前 - Oxidative stress is a fundamental factor in age-related changes. There must be a
common factor that reduces oxidative stress and promotes health … secrets of a healthy and long …

[HTML][HTML] Non-electrophilic NRF2 activators promote wound healing in human keratinocytes and diabetic mice and demonstrate selective downstream gene targeting

M Barakat, C Han, L Chen, BP David, J Shi, A Xu… - Scientific Reports, 2024 - nature.com
22 天前 - … skin exhibits increased oxidative stress and decreased NRF2 expression 33 .
Diabetic … (CDDO-Me), the preexisting NRF2 activator used as a positive control throughout this …

… -3p is associated with transforming growth factor-β1-induced oxidative stress and fibrosis by suppressing the NRF2 pathway in hypertensive diabetic kidney disease

SK Kim, GS Bae, T Bae, SK Ku, B Choi… - Free Radical Biology and …, 2024 - Elsevier
29 天前 - … Chronic kidney disease (CKD) is a global health problem characterized by
progressive renal fibrosis and excessive extracellular matrix deposition. Oxidative stress and …

[PDF][PDF] MULTI-TARGET EFFECTS OF CYCLOASTRAGENOL AND ITS DERIVATIVES ON AGE-RELATED PATHWAYS

S Yılmaz, PB Kırmızıbayrak, E Bedir - CMAPSEEC-2024, 2024 - cmapseec2024.com
29 天前 - … Update on the oxidative stress theory of aging: does oxidative stress play a role
in aging or healthy aging? Free Radical Biology and Medicine 48: 642-65. doi: 10.1016/j. …

The SIRT-1/Nrf2/HO-1 Axis: Guardians of Neuronal Health in Neurological Disorders

P Sethi, S Mehan, Z Khan, PK Maurya, N Kumar… - Behavioural Brain …, 2024 - Elsevier
42 天前 - Nrf2 is a transcription factor that regulates the genes … for oxidative stress response
and substance detoxification. The activation of Nrf2 guards cells against oxidative damage, …