[HTML][HTML] Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight
NF Abd El-Aal, RS Hamza, O Harb - Experimental parasitology, 2017 - Elsevier
Schistosomiasis is a chronic helminthic disease causing hepatic fibrosis. Some studies
demonstrated direct effect of targeting apoptosis on fibrosis regression. This study is a novel
trial of Paeoniflorin (PAE) on S. mansoni induced hepatic fibrosis in murine model compared
to Praziquantel (PZQ) evaluating their anti-parasitic and anti-fibrotic properties aiming to
discover a new therapy that decrease schistosomiasis morbidity. Thirty two laboratory bred
Swiss albino male CD-1 mice were used in this study. The mice were classified into four …
demonstrated direct effect of targeting apoptosis on fibrosis regression. This study is a novel
trial of Paeoniflorin (PAE) on S. mansoni induced hepatic fibrosis in murine model compared
to Praziquantel (PZQ) evaluating their anti-parasitic and anti-fibrotic properties aiming to
discover a new therapy that decrease schistosomiasis morbidity. Thirty two laboratory bred
Swiss albino male CD-1 mice were used in this study. The mice were classified into four …
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