Materials and Methods

Twenty-six resected cases of nodules from 23 patients with chronic hepatitis or cirrhosis caused by hepatitis B or

Abbreviations: GPC3, glypican-3; GS, Glutamine synthetase; HCC, hepatocellular carcinoma; H-DN, high-grade dysplastic nodule; HSP70, heat shock protein 70; ICGHN, The International Consensus Group for Hepatocellular Neoplasia; IWP, International Working Party; L-DN, low-grade dysplastic nodule. From the Department of Pathology, Kurume University, Kurume, Japan. Received June 11, 2008; accepted October 16, 2008. The International Consensus Group for Hepatocellular Neoplasia consists of: Masamichi Kojiro, Ian R. Wanless, Venancio Alves, Sunil Badve, Charles Balabaud, Pierre Bedosa, Prithi Bhathal, Paulette Bioulac-Sage, Elizabeth M. Brunt, Alastair D. Burt, John R. Craig, Amar Dhillon, Linda Ferrell, Stephen A. Geller, Zackary D. Goodman, Annette SH Gouw, Maria Guido, Maha Guindi, Prodromos Hytiroglou, Masayoshi Kage, Fukuo Kondo, Masutoshi Kudo, Gregory Y. Lauwers, Masayuki Nakano, Valerie Paradis, Young-Nyun Park, Alberto Quaglia, Massimo Roncalli, Tania Roskams, Boris Ruebner, Michiie Sakamoto, Romil Saxena, Neil D. Theise, Swan Thung, and Dina Taniakos. Address reprint requests to: Masamichi Kojiro, MD, Department of Pathology, Kurume University, 67 Asahi-machi, Kurume-shi 830-0011, Japan. E-mail: kojiro@ med. kurume-u. ac. jp; fax:(81)-942-31-7726. Copyright© 2008 by the American Association for the Study of Liver Diseases. Published online in Wiley InterScience (www. interscience. wiley. com). DOI 10.1002/hep. 22709