Background Nephrogenic systemic fibrosis is a fibrosing disorder associated with exposure
to gadolinium-based contrast agents in people with severely compromised renal function.
Objective The purpose of this study was to determine the reported number of cases of
nephrogenic systemic fibrosis in children using three distinct publicly available data sources.
Materials and methods We conducted systematic searches of the US Food and Drug
Administration Adverse Event Reporting System (FAERS), the International Center for …

Pediatric nephrogenic systemic fibrosis is rarely reported: a RADAR report … Nephrogenic
systemic fibrosis has been rarely reported in children. Although rules related to
confidentiality limit the ability to reconcile reports, active pharmaco-vigilance using RADAR (Research
on Adverse Drug events And Reports) methodology helped in establishing the number of
individual pediatric cases within the three major data sources. …