Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates
KM Reindl, MA Sheridan - … Biochemistry and Physiology Part A: Molecular …, 2012 - Elsevier
The growth hormone (GH)-insulin-like growth factor (IGF) system plays a major role in
coordinating the growth of vertebrates including fish. Considerable research on the
regulation of growth has focused on the production and secretion of GH from the pituitary.
This review will synthesize recent work on regulating extrapituitary aspects of the GH–IGF
system, which includes GH binding proteins (GHBP), GH receptors (GHR), IGF binding
protein (IGFBP), and IGF receptors (IGFR). These components are widely distributed and …
coordinating the growth of vertebrates including fish. Considerable research on the
regulation of growth has focused on the production and secretion of GH from the pituitary.
This review will synthesize recent work on regulating extrapituitary aspects of the GH–IGF
system, which includes GH binding proteins (GHBP), GH receptors (GHR), IGF binding
protein (IGFBP), and IGF receptors (IGFR). These components are widely distributed and …
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