Persistent circulating severe acute respiratory syndrome coronavirus 2 spike is associated with post-acute coronavirus disease 2019 sequelae
Clinical Infectious Diseases, 2023•academic.oup.com
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an
ongoing medical challenge. To identify biomarkers associated with PASC we analyzed
plasma samples collected from PASC and coronavirus disease 2019 patients to quantify
viral antigens and inflammatory markers. We detect severe acute respiratory syndrome
coronavirus 2 spike predominantly in PASC patients up to 12 months after diagnosis.
ongoing medical challenge. To identify biomarkers associated with PASC we analyzed
plasma samples collected from PASC and coronavirus disease 2019 patients to quantify
viral antigens and inflammatory markers. We detect severe acute respiratory syndrome
coronavirus 2 spike predominantly in PASC patients up to 12 months after diagnosis.
Abstract
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an ongoing medical challenge. To identify biomarkers associated with PASC we analyzed plasma samples collected from PASC and coronavirus disease 2019 patients to quantify viral antigens and inflammatory markers. We detect severe acute respiratory syndrome coronavirus 2 spike predominantly in PASC patients up to 12 months after diagnosis.
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