Enhancing the solubility of active drug ingredients is a major challenge faced by scientists
and researchers. Different approaches have been explored for the enhancement of solubility
and physicochemical properties of drugs, without affecting their stability or pharmacological
activity. Among the various strategies available, pharmaceutical co-crystals, co-amorphous
systems, and pharmaceutical salts as multicomponent systems (MCS) have gained interest
to improve physicochemical properties of drugs. Development of MCS by conventional …