Pharmacogenomics of cisplatininduced neurotoxicities: Hearing loss, tinnitus, and peripheral sensory neuropathy

X Zhang, MR Trendowski, E Wilkinson… - Cancer …, 2022 - Wiley Online Library
… A GWAS of cisplatin-induced peripheral neuropathy … three neurotoxicities (hearing loss,
tinnitus, and peripheral neuropathy). … with cisplatin-induced hearing loss, tinnitus, and peripheral

Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics

LB Travis, SD Fossa, HD Sesso… - Journal of the …, 2014 - academic.oup.com
… for Chemotherapy-Induced Long-Term Neurotoxicity score, which also includes self-reported
hearing loss and tinnitus… no other pharmacogenomic studies of CIPN in which cisplatin was …

Pharmacogenomics of cisplatin-induced neurotoxicities: Hearing loss, tinnitus and peripheral sensory neuropathy.

X Zhang, MR Trendowski, E Wilkinson, DR Feldman… - 2021 - ascopubs.org
chemotherapy for many cancers, but causes neurotoxicity, including hearing loss (CisHL),
tinnitus (CisTinn), and peripheral … comorbidities for cisplatin-induced neurotoxicities among …

Genetic and modifiable risk factors contributing to cisplatin-induced toxicities

MR Trendowski, O El Charif, PC Dinh Jr, LB Travis… - Clinical Cancer …, 2019 - AACR
… with cisplatin-induced ototoxicity and neurotoxicity because … in pharmacogenomic studies
related to cisplatin is likely due … contrast to hearing loss (a quantitative phenotype), peripheral

Clinical and genome-wide analysis of multiple severe cisplatin-induced neurotoxicities in adult-onset cancer survivors

MR Trendowski, HE Wheeler, O El-Charif… - Clinical Cancer …, 2020 - AACR
… Therefore, the incorporation of gene-based analyses in pharmacogenomic studies can be
… patients with severe hearing loss, tinnitus, and/or peripheral sensory neuropathy following …

Pharmacogenomics of cisplatin-induced ototoxicity

D Mukherjea, LP Rybak - Pharmacogenomics, 2011 - Taylor & Francis
… subjective hearing loss, ear pain and tinnitus Citation[11]. … Genotyping was carried out with
peripheral blood … , nephrotoxicity, neurotoxicity, ototoxicity and intellectual impairment. This …

[HTML][HTML] Systemic anticancer therapy-induced peripheral and central neurotoxicity: ESMO–EONS–EANO Clinical Practice Guidelines for diagnosis, prevention …

B Jordan, A Margulies, F Cardoso, G Cavaletti… - Annals of …, 2020 - Elsevier
… some degree of tinnitus during cisplatin-based ChT, and … to a lower incidence of
cisplatin-induced hearing loss without … thiosulfate against cisplatin-induced hearing loss in …

Clinical and genome-wide analysis of cisplatin-induced peripheral neuropathy in survivors of adult-onset cancer

ME Dolan, O El Charif, HE Wheeler, ER Gamazon… - Clinical Cancer …, 2017 - AACR
… These include hearing impairment, tinnitus, renal dysfunction, cardiovascular disease, …
to assess its role in the pathophysiology of neurotoxicity, possibly revealing novel targets. …

Chemotherapy-induced peripheral neuropathy: Current status and progress

JR Brewer, G Morrison, ME Dolan, GF Fleming - Gynecologic oncology, 2016 - Elsevier
… for Chemotherapy-Induced Long-Term Neurotoxicity score, which also includes self-reported
hearing loss and tinnitus… reported pharmacogenomic studies of CIPN in which cisplatin was …

Patient-reported functional impairment due to hearing loss and tinnitus after cisplatin-based chemotherapy

VA Sanchez, MM Shuey, PC Dinh Jr… - Journal of Clinical …, 2023 - ascopubs.org
hearing loss (HL) or tinnitus were more likely to fill out the questionnaire (eg, response bias),
we determined how many of the 371 patients had reported HL/tinnitus … -Term Neurotoxicity