Pharmacokinetics of first-line antituberculosis drugs in HIV-infected children with tuberculosis treated with intermittent regimens in India

G Ramachandran, AKH Kumar… - Antimicrobial Agents …, 2015 - Am Soc Microbiol
The objective of this report was to study the pharmacokinetics of rifampin (RMP), isoniazid
(INH), and pyrazinamide (PZA) in HIV-infected children with tuberculosis (TB) treated with a
thrice-weekly anti-TB regimen in the government program in India. Seventy-seven HIV-
infected children with TB aged 1 to 15 years from six hospitals in India were recruited.
During the intensive phase of TB treatment with directly observed administration of the
drugs, a complete pharmacokinetic study was performed. Drug concentrations were …

Pharmacokinetics of first-line antituberculosis drugs in HIV-infected children with tuberculosis treated with intermittent regimens in India.

GR Geetha Ramachandran, AKH Kumar, PK Bhavani… - 2015 - cabidigitallibrary.org
The objective of this report was to study the pharmacokinetics of rifampin (RMP), isoniazid
(INH), and pyrazinamide (PZA) in HIV-infected children with tuberculosis (TB) treated with a
thrice-weekly anti-TB regimen in the government program in India. Seventy-seven HIV-
infected children with TB aged 1 to 15 years from six hospitals in India were recruited.
During the intensive phase of TB treatment with directly observed administration of the
drugs, a complete pharmacokinetic study was performed. Drug concentrations were …
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