Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and …

SD Banister, M Longworth, R Kevin… - ACS Chemical …, 2016 - ACS Publications
… Indole and indazole synthetic cannabinoids (SCs) featuring l-valinate or l-tert-leucinate
pendant group have … Due to the limited pharmacological data available for these compounds, …

[PDF][PDF] The pharmacology of valinate and tert-leucinate synthetic cannabinoids

S Sachdev - 2016 - figshare.mq.edu.au
Synthetic cannabinoids (SCs) with indole or indazole cores and featuring L-valinate or L-tert
leucinate groups are epidemic recreational drugs in many parts of the world, and are …

Three fatalities associated with the synthetic cannabinoids 5F-ADB, 5F-PB-22, and AB-CHMINACA

V Angerer, S Jacobi, F Franz, V Auwärter… - Forensic science …, 2017 - Elsevier
… use of synthetic cannabinoids were reported. In this paper three death cases are described
with involvement of the synthetic cannabinoids 5F-PB-22, AB-CHMINACA, and 5F-ADB. The …

[HTML][HTML] Overview of synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA: clinical, analytical, and forensic implications

C Lobato-Freitas, AM Brito-da-Costa, RJ Dinis-Oliveira… - Pharmaceuticals, 2021 - mdpi.com
… the valinate side chain [29]. Chirality is common among SCs, implying different pharmacological
… AMB-FUBINACA and its 5F-ADB counterpart were also responsible for several non-fatal …

Structure-metabolism relationships of valine and tert-leucine-derived synthetic cannabinoid receptor agonists: a systematic comparison of the in vitro phase I …

F Franz, H Jechle, M Wilde, V Angerer, LM Huppertz… - Forensic …, 2019 - Springer
… 2 were recognized as promising pharmacological targets for … significant in five methyl valinate
SCs (5F-AMB-PINACA, AMB-… , valinamide, methyl tert-leucinate, methyl valinate, indicating …

Identification of a new tert-leucinate class synthetic cannabinoid in powder and “spice-like” herbal incenses: methyl 2-[[1-(5-fluoropentyl) indole-3-carbonyl] amino]-3 …

MDP Risseeuw, P Blanckaert, V Coopman… - Forensic science …, 2017 - Elsevier
… 5F-MDMB-PINACA (synonyms: 5F-ADB, MDMB(N)-2201), differing by the replacement …
pharmacology of valinate and tert-leucinate synthetic cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB

In vitro phase I metabolic profiling of the synthetic cannabinoids AM-694, 5F-NNEI, FUB-APINACA, MFUBINAC, and AMB-FUBINACA

O Apirakkan, I Gavrilović, DA Cowan… - Chemical Research in …, 2020 - ACS Publications
Synthetic cannabinoids (SCs) constitute one of the most rapidly expanding class of new …
Their pharmacology and toxicology are poorly understood, and the substances can be …

[HTML][HTML] Detection of a new tert-leucinate synthetic cannabinoid 5F-MDMB-PICA and its metabolites in human hair: application to authentic cases

Y Shi, L Zhou, L Li, M Liu, H Qiang, M Shen… - Frontiers in …, 2020 - frontiersin.org
… ) is a new synthetic cannabinoid characterized by valinate or tert-leucinate moieties. In recent
… Banister et al. for the purpose of pharmacological research on novel SCs characterized by …

Fourth generation of synthetic cannabinoid receptor agonists: A review on the latest insights

S Malaca, FP Busardò, G Nittari… - Current …, 2022 - ingentaconnect.com
… as pharmacology, toxicology, cannabinoid receptor agonists, … 5F-ADB-PINACA [50]. The
pharmaco-toxicological effects of this novel generation of fluorinated synthetic cannabinoids (5F-…

Cannabinoid-like effects of five novel carboxamide synthetic cannabinoids

MB Gatch, MJ Forster - Neurotoxicology, 2019 - Elsevier
… The chemical structures of the recent synthetic cannabinoids are unlike that of Δ 9 -THC,
but are largely based on the structure of older synthetic cannabinoids that are known to have …