With rising cases for the first time in years, malaria remains a significant public health
burden. The sexual stage of the malaria parasite infects mosquitoes to transmit malaria from
host to host. Hence, an infected mosquito plays an essential role in malaria transmission.
Plasmodium falciparum is the most dominant and dangerous malaria pathogen. Previous
studies identified a sexual stage-specific protein 16 (Pfs16) localized to the parasitophorous
vacuole membrane. Here, we elucidate the function of Pfs16 during malaria transmission …