Platelet-activating factor is a phospholipid with diverse potent physiological effects. Its actions
are achieved at concentrations as low as IO-‘” M in some systems and almost always by lo-’…

Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a
biologically active phospholipid mediator. Although PAF was named for its potential to induce …

Platelet-activating factor acetylhydrolases are structurally diverse isoenzymes that catalyze
the hydrolysis of the acyl group at the second position of glycerol in unusual, bioactive …

Platelet-activating factor (PAF) is a phospholipid mediator that belongs to a family of biologically
active, structurally related alkyl phosphoglycerides. PAF acts via a specific receptor that …

… Antigenic challenge of IgE-sensitised basophils releases a platelet-activating, factor (PAF),
probably a 1-lysophosphatidylcholine 5 . PAF has a potent action on rabbit 6,7 and human 8,…

The platelet-activating factor (PAF) produced and released by mast cells, basophils, neutrophils,
eosinophils, fibroblasts, platelets, endothelial cells, and even cardiac muscle cells plays …

… 'platelet-activating factor (PAF)' for the soluble factor released from basophils following IgE
stimulation. Several reports followed describing the lipid character of PAF [4-6]. However, it …

Platelet-activating factor (PAF) is a pro-inflammatory lipid mediator possessing a unique 1-O-alkyl
glycerophospholipid (GPC) backbone (IO-alkyl-2-acetyl-sn-glycero-3-phosphocholin). …

▪ Abstract Platelet-activating factor (PAF) is a phospholipid with potent, diverse physiological
actions, particularly as a mediator of inflammation. The synthesis, transport, and …

… This review focuses on recent developments in the field of platelet-activating factor (PAF),
with special emphasis on the stimuli and pathways that lead to PAF production, the …