Poly-lactide-co-glycolide nanoparticles containing voriconazole for pulmonary delivery: in vitro and in vivo study
B Sinha, B Mukherjee, G Pattnaik - … : Nanotechnology, Biology and Medicine, 2013 - Elsevier
Poly-lactide-co-glycolide nanoparticles (207–605 nm) containing voriconazole (VNPs) were
developed using a multiple-emulsification technique and were also made porous during
preparation in presence of an effervescent mixture for improved pulmonary delivery.
Pulmonary deposition of the particles was studied using a customized inhalation chamber.
VNPs had a maximum of 30%(w/w) drug loading and a zeta potential (ZP) value around− 20
mV. In the initial 2 hours, 20% of the drug was released from VNPs, followed by sustained …
developed using a multiple-emulsification technique and were also made porous during
preparation in presence of an effervescent mixture for improved pulmonary delivery.
Pulmonary deposition of the particles was studied using a customized inhalation chamber.
VNPs had a maximum of 30%(w/w) drug loading and a zeta potential (ZP) value around− 20
mV. In the initial 2 hours, 20% of the drug was released from VNPs, followed by sustained …
[PDF][PDF] Poly-lactide-co-glycolide nanoparticles containing voriconazole for pulmonary delivery: in vitro and in vivo study
MP Biswadip Sinha, B Mukherjee, G Pattnaik - 2012 - academia.edu
Poly-lactide-co-glycolide nanoparticles (207–605 nm) containing voriconazole (VNPs) were
developed using a multiple-emulsification technique and were also made porous during
preparation in presence of an effervescent mixture for improved pulmonary delivery.
Pulmonary deposition of the particles was studied using a customized inhalation chamber.
VNPs had a maximum of 30%(w/w) drug loading and a zeta potential (ZP) value around− 20
mV. In the initial 2 hours, 20% of the drug was released from VNPs, followed by sustained …
developed using a multiple-emulsification technique and were also made porous during
preparation in presence of an effervescent mixture for improved pulmonary delivery.
Pulmonary deposition of the particles was studied using a customized inhalation chamber.
VNPs had a maximum of 30%(w/w) drug loading and a zeta potential (ZP) value around− 20
mV. In the initial 2 hours, 20% of the drug was released from VNPs, followed by sustained …
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