Porcine PD‐L1: cloning, characterization, and implications during xenotransplantation
Background: Effective intervention achieved by manipulating cell‐mediated xenogeneic
immune responses would critically increase the clinical feasibility of xenotransplantation as
immediate hyperacute rejections become controllable through genetic modulations of donor
organs. Endogenous negative regulatory signals like the programmed death 1 (PD‐1)‐
programmed death ligand 1 (PD‐L1) system are candidate targets for the control of cell‐
mediated xenogeneic immune response. Methods: A porcine PD‐L1 molecule was cloned …
immune responses would critically increase the clinical feasibility of xenotransplantation as
immediate hyperacute rejections become controllable through genetic modulations of donor
organs. Endogenous negative regulatory signals like the programmed death 1 (PD‐1)‐
programmed death ligand 1 (PD‐L1) system are candidate targets for the control of cell‐
mediated xenogeneic immune response. Methods: A porcine PD‐L1 molecule was cloned …
Porcine PD-L1: cloning, characterization, and implications during xenotransplantation.
JDH Jeon DaeHyun, OKH Oh KeunHee, BC Oh… - 2007 - cabidigitallibrary.org
Background: Effective intervention achieved by manipulating cell-mediated xenogeneic
immune responses would critically increase the clinical feasibility of xenotransplantation as
immediate hyperacute rejections become controllable through genetic modulations of donor
organs. Endogenous negative regulatory signals like the programmed death 1 (PD-1)-
programmed death ligand 1 (PD-L1) system are candidate targets for the control of cell-
mediated xenogeneic immune response. Methods: A porcine PD-L1 molecule was cloned …
immune responses would critically increase the clinical feasibility of xenotransplantation as
immediate hyperacute rejections become controllable through genetic modulations of donor
organs. Endogenous negative regulatory signals like the programmed death 1 (PD-1)-
programmed death ligand 1 (PD-L1) system are candidate targets for the control of cell-
mediated xenogeneic immune response. Methods: A porcine PD-L1 molecule was cloned …
以上显示的是最相近的搜索结果。 查看全部搜索结果