Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment

H Ohashi, K Watashi, W Saso, K Shionoya, S Iwanami… - Iscience, 2021 - cell.com
nelfinavir will shorten the period until viral clearance by 4.9 days and the combining
cepharanthine/nelfinavir enhanced theirpotential anti-SARS-CoV-2 activity of cepharanthine and …

[PDF][PDF] Identification of Anti-COVID-19 Agents, Cepharanthine and Nelfinavir, and Their Potential Usage for Combination Treatment

H Ohashi, K Watashi, W Saso, K Shionoya, S Iwanami… - 2020 - researchgate.net
drugs predicts that Nelfinavir will shorten the period until viral 63 clearance by 4.9-days and
the combining Cepharanthine/Nelfinavir enhanced their … multidrug combination treatment for …

[PDF][PDF] … of pharmacokinetic drug-drug interaction and dosage regimens optimization of nelfinavir and cepharanthine as a potential combination against COVID-19.

W Nosoongnoen - Pharmaceutical Sciences Asia, 2023 - pharmacy.mahidol.ac.th
… Therefore, in this study, the potential dosage regimens would be nelfinavir 500 mg every …
Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination

Cepharanthine: A review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

M Rogosnitzky, P Okediji, I Koman - Pharmacological Reports, 2020 - Springer
… existing drugs such as cepharanthine (CEP) as potential … of CEP as a potential anti-COVID-19
medication. This review is … combined with other antiviral medications (such as nelfinavir

The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against …

B Xia, L Zheng, Y Li, W Sun, Y Liu, L Li… - Frontiers in …, 2023 - frontiersin.org
… research and development of anti-COVID-19 medication, this … In this study, they demonstrated
that CEP and nelfinavir (NFV)… of CEP in combination with FDA-approved nelfinavir inhibits …

Pharmacological effects and clinical prospects of cepharanthine

D Liang, Q Li, L Du, G Dou - Molecules, 2022 - mdpi.com
anti-COVID-19 activity of cepharanthine has been confirmed repeatedly [25,26]. The combined
use of nelfinavir and cepharanthinedrugs in vitro, which revealed that cepharanthine had …

Natural products, alone or in combination with FDA-approved drugs, to treat COVID-19 and lung cancer

L Yang, Z Wang - Biomedicines, 2021 - mdpi.com
… the potential importance of natural products, including their … of potential anti-COVID-19
or anti-lung cancer agents. To … the critical value of cepharanthine and nelfinavir in anti-SARS-…

[PDF][PDF] Natural products, alone or in combination with FDA-approved drugs, to treat COVID-19 and lung cancer. Biomedicines 2021, 9, 689

L Yang, Z Wang - Therapeutic Potential of Plant Secondary Metabolites …, 2021 - core.ac.uk
… the potential importance of natural products, including their … of potential anti-COVID-19
or anti-lung cancer agents. To … the critical value of cepharanthine and nelfinavir in anti-SARS-…

[HTML][HTML] Unraveling the mechanism of action of cepharanthine for the treatment of novel coronavirus pneumonia (COVID-19) from the perspectives of systematic …

F Sun, J Liu, A Tariq, Z Wang, Y Wu, L Li - Arabian Journal of Chemistry, 2023 - Elsevier
… of specific drugs, there is still a need for further development of more effective specific …
anti-COVID-19 effects when used alone or in combination with nelfinavir (Ohashi et al., 2021…

Progress in the study of antiviral activity of cepharanthine against SARS-CoV-2

H Fan, K Liu, B Hong, S He, P Han, M Li… - … Fang yi ke da xue xue …, 2022 - europepmc.org
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