Pregnenolone: Summary Report

SL Gianturco, LL Pavlech, KD Storm, SJ Yoon… - 2020 - archive.hshsl.umaryland.edu
… to establish the availability of pregnenolone products in the … for pregnenolone; name variations
of pregnenolone were … (OTC) products containing pregnenolone. The availability of OTC …

Pregnenolone

E HENDERSON, M WEINBERG… - The Journal of Clinical …, 1950 - academic.oup.com
… are briefly summarized reports of therapeutic trials with parenteral pregnenolone, of which we
Reports of this nature are so at variance with the experience of other groups of … SUMMARY

A randomized, double-blind, placebo-controlled trial of pregnenolone for bipolar depression

ES Brown, J Park, CE Marx, LS Hynan… - …, 2014 - nature.com
… In the current report, the effect of the neurosteroid pregnenolone on depressive symptoms
in … In summary, pregnenolone was associated with a reduction in the primary outcome …

Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence

CE Marx, DW Bradford, RM Hamer, JC Naylor, TB Allen… - Neuroscience, 2011 - Elsevier
… This review will provide a summary of emerging preclinical … pregnenolone and selected
pregnenolone metabolites—specifically … report initial encouraging findings for pregnenolone as a …

THE USE OF Δ5-PREGNENOLONE IN VARIOUS CLINICAL DISORDERS

TH McGAVACK, J CHEVALLEY… - The Journal of Clinical …, 1951 - academic.oup.com
… Recent reports (7, 12, 13, 17, 28-30) indicate that pregnenolone is clinically effective in the
… diseases mentioned in the summary table (Table 4). The ability of pregnenolone to affect the …

Pregnenolone for cognition and mood in dual diagnosis patients

IJ Osuji, E Vera-Bolaños, TJ Carmody, ES Brown - Psychiatry research, 2010 - Elsevier
… In summary, available data, although … and pregnenolone supplementation may result in
symptomatic improvement. In this report, we explored the effects of 8 weeks of pregnenolone

Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia

CE Marx, J Lee, M Subramaniam, A Rapisarda… - …, 2014 - Springer
… There are also a number of studies reporting enhanced learning and memory in rodent …
Summary In summary, adjunctive pregnenolone significantly improved functional capacity …

Effect of pregnenolone vs placebo on self-reported chronic low back pain among US military veterans: A randomized clinical trial

JC Naylor, JD Kilts, LJ Shampine, GJ Parke… - JAMA network …, 2020 - jamanetwork.com
… Individuals randomized to pregnenolone were 2.6 times more likely to report a reduction in
pain intensity ratings of 20% or greater by both pain diary (OR, 2.62; 95% CI, 1.06-6.50; P = .…

[PDF][PDF] State of California Decrees Strong Warning Labels on DHEA and Pregnenolone

J Trevano - 2011 - livinternational.com
… Similarly, there is no published report of either DHEA or pregnenolone in association
with any visual disturbance or glaucoma. Just two reports exist on age-related macular …

Deficient pregnenolone synthesis associated with congenital adrenal hyperplasia and organelle dysfunction

HS Bose, AM Rice, B Marshall… - … Case Reports, 2019 - edm.bioscientifica.com
… In summary, we conclude that an absence of required pregnenolone secretion affected
organelle … In summary, the absence of pregnenolone secretion altered mitochondrial membrane …