Preliminary toxicity analysis of 3-dimensional conformal radiation therapy versus intensity modulated radiation therapy on the high-dose arm of the Radiation Therapy …

JM Michalski, Y Yan, D Watkins-Bruner… - International Journal of …, 2013 - Elsevier
Purpose To give a preliminary report of clinical and treatment factors associated with toxicity
in men receiving high-dose radiation therapy (RT) on a phase 3 dose-escalation trial.
Methods and Materials The trial was initiated with 3-dimensional conformal RT (3D-CRT)
and amended after 1 year to allow intensity modulated RT (IMRT). Patients treated with 3D-
CRT received 55.8 Gy to a planning target volume that included the prostate and seminal
vesicles, then 23.4 Gy to prostate only. The IMRT patients were treated to the prostate and …
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