[HTML][HTML] Preoperative alpha-fetoprotein (AFP) in hepatocellular carcinoma (HCC): is this 50-year biomarker still up-to-date?
F Muscari, C Maulat - Translational Gastroenterology and …, 2020 - ncbi.nlm.nih.gov
UICC staging) and tumor size. Although this study is retrospective, it is of interest both by the
issue raised which is still contradictory and by the large size of the cohort studied by the
authors (1,182 patients). The authors showed that a high AFP rate was correlated with poor
OS and DFS, whereas patients with low AFP rate had better prognosis. The median DFS
were 55.6, 25 and 8.4 months for HCC patients with AFP< 20, 20–400 and> 400 ng/mL
respectively (P< 0.001). The median OS were 132.9, 77.2 and 38.4 months respectively (P< …
issue raised which is still contradictory and by the large size of the cohort studied by the
authors (1,182 patients). The authors showed that a high AFP rate was correlated with poor
OS and DFS, whereas patients with low AFP rate had better prognosis. The median DFS
were 55.6, 25 and 8.4 months for HCC patients with AFP< 20, 20–400 and> 400 ng/mL
respectively (P< 0.001). The median OS were 132.9, 77.2 and 38.4 months respectively (P< …
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