Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
Importance Amyloid-β positron emission tomography (PET) imaging allows in vivo detection
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its
diagnostic utility is still unclear because amyloid plaques also occur in patients with non–AD
dementia. Objective To use individual participant data meta-analysis to estimate the
prevalence of amyloid positivity on PET in a wide variety of dementia syndromes. Data
Sources The MEDLINE and Web of Science databases were searched from January 2004 to …
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its
diagnostic utility is still unclear because amyloid plaques also occur in patients with non–AD
dementia. Objective To use individual participant data meta-analysis to estimate the
prevalence of amyloid positivity on PET in a wide variety of dementia syndromes. Data
Sources The MEDLINE and Web of Science databases were searched from January 2004 to …
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