Prevalence of coagulation factor XIII and plasminogen activator inhibitor-1 gene polymorphisms among Egyptian women suffering from unexplained primary recurrent …
IR Elmahgoub, RA Afify, AAA Aal… - Journal of Reproductive …, 2014 - Elsevier
Recurrent miscarriage (RM) is an obstetric challenge. Polymorphisms of factor XIII (FXIII)
and plasminogen activator inhibitor-1 (PAI-1) may cause an imbalance between coagulation
and fibrinolysis that can end in RM. The aim of the work was to determine the prevalence of
FXIII Val34Leu and PAI-1 4G/5G gene polymorphisms in Egyptian women presenting with
unexplained primary first trimester RM. Genotyping of 120 unexplained primary first trimester
RM patients and 130 healthy controls by polymerase chain reaction (PCR) amplification of …
and plasminogen activator inhibitor-1 (PAI-1) may cause an imbalance between coagulation
and fibrinolysis that can end in RM. The aim of the work was to determine the prevalence of
FXIII Val34Leu and PAI-1 4G/5G gene polymorphisms in Egyptian women presenting with
unexplained primary first trimester RM. Genotyping of 120 unexplained primary first trimester
RM patients and 130 healthy controls by polymerase chain reaction (PCR) amplification of …
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