[HTML][HTML] Preventing esophageal stricture after endoscopic submucosal dissection: steroid injection and shielding with polyglycolic acid sheets and fibrin glue

Y Kataoka, Y Tsuji, Y Sakaguchi, S Kodashima… - …, 2015 - thieme-connect.com
Y Kataoka, Y Tsuji, Y Sakaguchi, S Kodashima, N Yamamichi, M Fujishiro, K Koike
Endoscopy, 2015thieme-connect.com
Postoperative stricture after endoscopic submucosal dissection (ESD) for esophageal
neoplasms is a major complication; Ono et al. have reported that stricture occurs in 90% of
cases in which the circumferential extent of a lesion comprises more than two-thirds of the
esophagus [1]. Several methods for preventing stricture, such as endoscopic balloon dilation
(EBD), intralesional steroid injection, and oral steroid therapy, have previously been
reported, but each method has its own drawbacks. Sakaguchi et al. recently reported that a …
Postoperative stricture after endoscopic submucosal dissection (ESD) for esophageal neoplasms is a major complication; Ono et al. have reported that stricture occurs in 90% of cases in which the circumferential extent of a lesion comprises more than two-thirds of the esophagus [1]. Several methods for preventing stricture, such as endoscopic balloon dilation (EBD), intralesional steroid injection, and oral steroid therapy, have previously been reported, but each method has its own drawbacks.
Sakaguchi et al. recently reported that a novel endoscopic method of shielding with polyglycolic acid (PGA) sheets and fibrin glue reduced the number of EBD sessions [2], but stricture still occurred at a rate of 37.5%. Here, we report a case of successful prevention of stricture following a large esophageal ESD with the combination of intralesional steroid injection and shielding with PGA sheets and fibrin glue.
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